Bibliographie Ainat :
1 – A complex of three natural anti-inflammatory agents (Ainat) provides relevant relief of pain in patients with osteoarthritis : results of an observational survey in daily practice conditions Thierry Conrozier; Pierre Mathieu, Monique Bonjean, Jean-François Marc, Jean-Luc Renevier, Jean-Charles Balblanc – Alternative therapies, Vol.20, Suppl. 1, 2012
Brochard S, Pontin J, Bernay B, et al. The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells. BMC Complement Med Ther. 2021 Oct 14;21(1):261. doi: 10.1186/s12906-021-03435-7.
Bibliographie Cuivramine :
1 – Impact of the Addition of Ginger Extract and Copper Sulphate to
Glucosamine Sulphate on IL-1β-Stimulated Chondrocytes – Rousset et al.
J Rheum Dis Treat 2016, 2:038
2 – Predictive factors of adherence to an association of glucosamine sulfate, copper, and ginger extracts in patients with symptomatic osteoarthritis: a prospective open-label French noninterventional study (the PREDOA study)
Conrozier et al. Patient Preference and Adherence 2019:13 915–921
Bibliographie HappyCross :
1-Conrozier T. Is the addition of a polyol to hyaluronic acid a significant advance in the treatment of osteoarthritis? Curr Rheumatol Rev. 2017. doi: 10.2174/1573397113666170710115558
MANNITOL
2-Conrozier T, Mathieu P, Rinaudo M. Mannitol Preserves the Viscoelastic Properties of Hyaluronic Acid in an In Vitro Model of Oxidative Stress. Rheumatol Ther. 2014;1(1):45-54.
3-Cavone L, Calosi L, Cinci L et al. Topical mannitol reduces inflammatory edema in a rat model of arthritis. Pharmacology 2012; 89:18-21. doi: 10.1159/000335094
GENOU
4-Henrotin Y, Berenbaum F, Chevalier X et al. Reduction of the Serum Levels of a Specific Biomarker of Cartilage Degradation (Coll2-1) by Hyaluronic Acid (KARTILAGE® CROSS) Compared to Placebo in Painful Knee Osteoarthritis Patients: the EPIKART Study, a Pilot Prospective Comparative Randomized Double Blind Trial. BMC Musculoskelet Disord. 2017 May 26;18(1):222. doi: 10.1186/s12891-017-1585-2.
5- Monet M, Bozgan AM, Conrozier T. Safety and Efficacy of Single Intra-Articular Injection of a Cross-Linked Hyaluronic Acid/Mannitol Formulation [Happycross®] in knee Osteoarthritis Results of a Prospective Observational Study in Daily Practice Conditions. Ortho Rheum open Access 2017; 5 ( 3 ) DOI: 10.19080/OROAJ.2017.05.55566
6-Conrozier T, Monet M, Lohse A, Raman R. Getting Better or Getting Well? The Patient Acceptable Symptom State (PASS) Better Predicts Patient’s Satisfaction than the Decrease of Pain, in Knee Osteoarthritis Subjects Treated with Viscosupplementation. Cartilage. 2018;9(4):370-377. doi: 10.1177/1947603517723072.
7- Perruchet S, Balblanc JC, Rapp C, et al. The Association between Radiographic Features and the Duration of Effectiveness of a Single Injection of Extended-Release Hyaluronic Acid (HANOX-M-XL) in Patients with Knee Osteoarthritis: Preliminary Results of a Prospective Trial. Cartilage. 2023 Jun;14(2):136-143. doi: 10.1177/19476035221109230.
HANCHE
8-Eymard F, Maillet B, Lellouche H et al. Predictors of response to viscosupplementation in patients with hip osteoarthritis: results of a prospective, observational, multicentre, open-label, pilot study. BMC Musculoskelet Disord. 2017;18(1):3. doi: 10.1186/s12891-016-1359-2.
CHEVILLE
9- Bossert M, Boublil D, Parisaux JM, et al. Imaging Guidance Improves the Results of Viscosupplementation with HANOX-M-XL in Patients with Ankle Osteoarthritis: Results of a Clinical Survey in 50 Patients Treated in Daily Practice. Clin Med Insights Arthritis Musculoskelet Disord. 2016;9:195-199
Bibliographie HappyVisc :
Conrozier T, Eymard F, Afif N et al; Happyvisc Study Group. Safety and efficacy of intra-articular injections of a combination of hyaluronic acid and mannitol (HAnOX-M) in patients with symptomatic knee osteoarthritis: Results of a double-blind, controlled, multicenter, randomized trial. Knee. 2016 Oct;23(5):842-8. doi: 10.1016/j.knee.2016.05.015.
Tiendrebeogo E, Choueiri M, Chevalier X et al. Does the Presence of Neuropathic Pain Influence the Response to Hyaluronic Acid in Patients with Knee Osteoarthritis? Cartilage. 2021 Dec;13(1_suppl):1548S-1556S. doi: 10.1177/1947603520954509.
Eymard F, Chevalier X, Conrozier T. Obesity and radiological severity are associated with viscosupplementation failure in patients with knee osteoarthritis. J Orthop Res. 2017 Oct;35(10):2269-2274. doi: 10.1002/jor.23529.
Conrozier T, Eymard F, Chouk M, Chevalier X. Impact of obesity, structural severity and their combination on the efficacy of viscosupplementation in patients with knee osteoarthritis. BMC Musculoskelet Disord. 2019 Aug 17;20(1):376. doi: 10.1186/s12891-019-2748-0.
Eymard F, Bossert M, Lecurieux Ret al. Addition of Mannitol to Hyaluronic Acid may Shorten Viscosupplementation Onset of Action in Patients with Knee Osteoarthritis: Post-Hoc Analysis of A Double-blind, Controlled Trial. J Clin Exp Orthop 2016; 2: 21. doi: 10.4172/2471-8416.100021
Bibliographie HappyMini :
Baron D, Baron H, Baerer C et al. Predictors for patient satisfaction of a single intra-articular injection of crosslinked hyaluronic acid combined with mannitol (HANOX-M-XL) in patients with temporomandibular joint osteoarthritis. Results of a prospective open-label pilot study (HAPPYMINI-ARTEMIS trial). BMC Musculoskelet Disord. 2022 ;23(1):392. doi: 10.1186/s12891-022-05352-3.
Galois L, Coillard JY, Porterie J, et al. Open-Label Pilot Study of a Single Intra-Articular Injection of Mannitol-Modified Cross-Linked Hyaluronic Acid (HANOX-M-XL) for the Treatment of the First Metatarsophalangeal Osteoarthritis (Hallux Rigidus): The REPAR Trial. Clin Med Insights Arthritis Musculoskelet Disord. 2022;15:11795441211055882. doi: 10.1177/11795441211055882.
Dauvissat J, Rizzo C, Lellouche H, et al. Safety and Predictive Factors of Short-Term Efficacy of a Single Injection of Mannitol-Modified Cross-Linked Hyaluronic Acid in Patients with Trapeziometacarpal Osteoarthritis. Results of a Multicentre Prospective Open-Label Pilot Study (INSTINCT Trial). Clin Med Insights Arthritis Musculoskelet Disord. 2018;11:1179544118782901. doi: 10.1177/1179544118782901.
